Mulberry may reshape gut bacteria and influence metabolism

Mulberry compounds may reshape the gut microbiome in ways that support intestinal health and metabolism, with some combinations showing especially strong effects in animal studies. The results vary depending on the plant part and processing method, and the benefits have yet to be confirmed in humans. Mulberry may reshape gut bacteria and influence metabolism.

Now, researchers are examining whether compounds in the plant can alter the gut microbiota and, in turn, affect metabolism. A review involving scientists from Wroclaw Medical University suggests that the results may depend heavily on the mulberry species, which part of the plant is used, and how it is processed. "The gut microbiota not only contributes to the functioning of the gastrointestinal tract but may also influence metabolism throughout the body.

Mulberry is particularly interesting in this respect because it contains many bioactive compounds, including polyphenols and polysaccharides, which may interact with gut microorganisms," explains Anna Prescha, PhD, DSc, Professor at Wroclaw Medical University, from the Department of Dietetics and Bromatology. Different Mulberries Contain Different Compounds Research to date has concentrated mostly on white mulberry ( Morus alba), although black mulberry ( Morus nigra), especially its fruit, has also produced notable results. Mulberry leaves contain several biologically active substances, including 1-deoxynojirimycin (DNJ), which is known to affect carbohydrate metabolism, along with polyphenols and polysaccharides.