Scientists discovered that disrupting the chemical messages bacteria use to communicate can push dental plaque toward a healthier microbial balance. The approach could lead to new treatments for gum disease that control harmful bacteria without destroying beneficial species. A new way to fight gum disease without wiping out good bacteria.
When microbial communication is “on”, disease-associated species grow (left). Disrupting this communication (right) promotes health-associated bacteria. That ability helps them survive changing conditions, but it can also create problems when harmful species become resistant to antibiotics and disinfectants.
At the same time, bacteria are not simply enemies to eliminate. Many species play important roles in human health, including the hundreds of different microbes that live in the mouth. That raises an intriguing possibility: instead of trying to kill bacteria, could scientists influence how they behave and encourage healthier microbial communities.
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