Association between postoperative serum calcium and complications after pancreaticoduodenectomy in a retrospective multicenter study. Download PDF Abstract Serum calcium is an important indicator for assessing the severity of acute pancreatitis. The physiological processes following pancreatitis and pancreaticoduodenectomy (PD) are similar; however, it is unknown whether serum calcium is associated with outcomes after PD.
The present study analyzed serum calcium on postoperative days 3, 6, 9, and 12. Logistic regression was used to identify correlations between serum calcium, clinical postoperative pancreatic fistula (POPF), and other complications. Generalized additive models (GAM) were used to determine serum calcium thresholds.
Restricted cubic spline (RCS) was used to visualize linear or non-linear relationships between serum calcium and outcomes. Latent class analysis (LCA) was used to identify potential categories based on serum calcium levels at various time points. Generalized additive mixed-effects models (GAMM) were combined to analyze the relationship between serum calcium and outcomes at four-time points.
Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with qualified healthcare professionals for medical decisions and treatment options.
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