Health

Serum uric acid and lipid profiles among type 2 diabetes patients with cardiovascular disease at Dessie Comprehensive Specialized Hospital

Serum uric acid and lipid profiles among type 2 diabetes patients with cardiovascular disease at Dessie Comprehensive Specialized Hospital. Download PDF Abstract One of the most common causes of cardiovascular disease (CVD) is diabetes. Hyperuricemia will increase the production of reactive oxygen species (ROS), which cause inflammation and vessel dysfunction, and abnormalities in plasma lipid and lipoprotein levels will result in atherosclerosis, which is the process of causing CVD.

If not treated in a timely manner, hyperuricemia and dyslipidemia are highly related to CVD in diabetic patients and can greatly increase mortality and morbidity from diabetes. Therefore, this study aimed to evaluate serum uric acid and lipid profiles among T2DM patients with CVD in Dessie Comprehensive Specialized Hospital, Northeastern Ethiopia. A comparative cross-sectional study was conducted at Dessie Comprehensive Specialized Hospital with 90 participants in each group.

Data were collected using a semi-structured questionnaire, and serum uric acid, FBS, lipid profile, and creatinine were measured using a clinical chemistry analyzer. Data were entered into EpiData 4.6 and analyzed using STATA 14. Group differences were assessed using one-way ANOVA and post hoc tests, while Pearsonโ€™s correlation was used to assess associations between uric acid, lipid profile, and other parameters.

Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with qualified healthcare professionals for medical decisions and treatment options.


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