Trajectories of body roundness index and risk of incident hyperuricemia in middle-aged and older Chinese adults: evidence from the China Health and Retirement Longitudinal Study

Trajectories of body roundness index and risk of incident hyperuricemia in middle-aged and older Chinese adults: evidence from the China Health and Retirement Longitudinal Study. Download PDF Abstract The body roundness index (BRI) is an emerging anthropometric indicator of abdominal obesity. The longitudinal association between BRI trajectories and the risk of hyperuricemia remains unclear.

This study aimed to examine the association between long-term BRI trajectories and incident hyperuricemia among middle-aged and older Chinese adults. This prospective cohort study included 4565 participants aged ≥ 45 years from the China Health and Retirement Longitudinal Study (CHARLS) who were free of hyperuricemia at baseline. Group-based trajectory modeling was used to identify distinct BRI trajectories across the 2011, 2013, and 2015 waves.

Multivariable logistic regression models were applied to estimate odds ratios for hyperuricemia assessed at the 2015 follow-up, with Model 2 (adjusting for demographic and lifestyle factors) designated as the primary model. Four distinct BRI trajectories were identified: low (19.2%), moderate-low (35.9%), moderate-high (28.8%), and high (16.1%). At the 2015 assessment, 458 participants (10.03%) were identified with hyperuricemia.

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